The 3,500 m2 (38,000 sq ft) museum occupies the lower three floors of the renovated Haus zur Enge, a ten-story mixed-use building located in the Enge quarter, across from the Zurich Enge railway station and the FIFA-owned Hotel Ascot. The building also contains a sports bar, a bistro, a café, a library, a museum shop and conference rooms; the upper floors have office spaces and 34 luxury apartments.

The museum exhibits over one thousand objects. These include memorabilia from every FIFA World Cup and FIFA Women's World Cup, the most famous one being the original FIFA World Cup Trophy. The exhibition features various interactive and multimedia installations such as the biggest pinball machine ever made and an audiovisual media installation called Visions of Football using 8 metres (26 ft) LED screens. In 2017, the museum was nominated for the German Design Award.

Every year, the museum participates in Zurich's Long Night of Museums.